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eMedicine - Fracture, Tibia and Fibula : Article by

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Author: Jeffrey G Norvell, MD, Clinical Assistant Professor of Emergency Medicine, University of Kansas School of Medicine

Jeffrey G Norvell is a member of the following medical societies: American College of Emergency Physicians and Society for Academic Emergency Medicine

Coauthor(s): Mark Steele, MD, Associate Dean for Truman Medical Center Programs, Professor, Department of Emergency Medicine, University of Missouri-Kansas City

Editors: Michelle Ervin, MD, Chair, Department of Emergency Medicine, Howard University Hospital; Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine; David B Levy, DO, FACEP, FAAEM, Chairman, Department of Emergency Medicine, St Elizabeth Health Center; Associate Professor of Emergency Medicine, Northeastern Ohio Universities College of Medicine; John D Halamka, MD, MS, Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center; Rick Kulkarni, MD, Medical Director, Assistant Professor of Surgery, Section of Emergency Medicine, Yale-New Haven Hospital

Author and Editor Disclosure

Synonyms and related keywords: lower leg fracture, broken leg, long bone fracture, popliteal artery injury, compartment syndrome, gangrene, osteomyelitis, injury to the peroneal nerve, foot drop, delayed union, fracture nonunion, arthritis, toddler fracture, distal spiral fracture of tibia

Background

Lower leg fractures include fractures of the tibia and fibula. Of these two bones, the tibia is the only weightbearing bone. Fractures of the tibia generally are associated with fibula fracture, because the force is transmitted along the interosseous membrane to the fibula.

The skin and subcutaneous tissue are very thin over the anterior and medial tibia and as a result of this, a significant number of fractures to the lower leg are open. Even in closed fractures, the thin, soft tissue can become compromised. In contrast, the fibula is well covered by soft tissue over most of its course with the exception of the lateral malleolus.

The tibia and fibula articulate at the proximal tibia-fibular syndesmosis.

Fractures of the tibia can involve the tibial plateau, tibial tubercle, tibial eminence, proximal tibia, tibial shaft, and tibial plafond.

For more information, see Medscape's Trauma Resource Center.

Frequency

United States

Fractures of the tibia are the most common long bone fractures. Isolated midshaft or proximal fibula fractures are uncommon.

Mortality/Morbidity

  • Limb loss may occur as a result of severe soft-tissue trauma, neurovascular compromise, popliteal artery injury, compartment syndrome, or infection such as gangrene or osteomyelitis. Popliteal artery injury is a particularly serious injury that threatens the limb and is easily overlooked.
  • The common peroneal nerve crosses the fibular neck. This nerve is susceptible to injury from a fibular neck fracture, the pressure of a splint, or during surgical repair. This can result in foot drop and sensation abnormalities.
  • Delayed union, nonunion, and arthritis may occur. Among the long bones, the tibia is the most common site of fracture nonunion.

Age

Toddler fracture (distal spiral fracture of the tibia) is most common in children aged 9 months to 3 years.



History

  • Mechanisms of injury for tibia-fibula fractures can be divided into 2 categories:
    • Low-energy injuries such as ground levels falls and athletic injuries
    • High-energy injuries such as motor vehicle injuries, pedestrians struck by motor vehicles, and gunshot wounds
  • Patient may report a history of direct (motor vehicle crash or axial loading) or indirect (twisting) trauma.
  • Patient may complain of pain, swelling, and inability to ambulate with tibia fracture.
  • Ambulation is possible with isolated fibula fracture.
  • Tibial plateau fractures occur from axial loading with valgus or varus forces, such as in a fall from a height or collision with the bumper of a car. The lateral tibial plateau is fractured more frequently than the medial plateau.
  • Tibial tubercle fractures usually occur during jumping activities such as basketball, diving, football, and gymnastics. This type of fracture is more common in adolescents than in adults.
  • Tibial eminence fractures occur with trauma to the distal femur while the knee is flexed such as falling off of a bicycle. Another mechanism for this fracture is hyperextension. Tibial eminence avulsion fractures occur most often in children aged 8-14 years but can occur in a skeletally mature patient.
  • Tibial shaft fractures usually present with a history of major trauma. An exception to this is a toddler's fracture, which is a spiral fracture that occurs with minor trauma in children who are learning to walk.
  • Tibial plafond fractures refer to fractures involving the weightbearing surface of the distal tibia. This type of injury usually results from high-energy axial loading but may result from lower-energy rotation forces.
  • Maisonneuve fractures are rare and considered unstable ankle injuries. This type of injury usually involves a pronation-external rotation force.
  • Stress fractures of the tibia and fibula may occur as a result of repetitive submaximal stresses that may occur while participating in athletics. The history may reveal some change in training routine.

Physical

  • When examining a patient for a lower leg fracture one should first examine the patient for edema, ecchymosis, and point tenderness. Gross deformities should be noted and splinted. A careful neurovascular assessment should be performed, and an emergent fracture reduction should be performed if neurovascular deficits are present.
  • A careful examination should be performed for open wounds. Open fractures require antibiotics and an emergent orthopedic consultation.
  • Tibial plateau fractures often present with a knee effusion. Tenderness will be present along the medial or lateral tibial plateau. Approximately 20% of tibial plateau fractures are associated with ligamentous injuries.
  • Tibial tubercle fracture will have tenderness over the anterior tibia approximately 3 cm distal to the articular surface. In more severe tibial tubercle fractures, full extension of the knee is not possible. The patella may be high riding.
  • Tibial eminence fracture may present with a knee effusion and pain and may represent an avulsion of the tibial attachment of the anterior cruciate ligament.
  • Tibial shaft fractures are the most common long bone fracture and usually involve the fibula as well. Tibial fractures present with localized pain, swelling, and deformity.
  • Maisonneuve fractures involve a fracture of the proximal fibula in association with a fractured medial malleolus (or injured deltoid ligament) and diastasis of the distal tibiofibular syndesmosis. Patients present with proximal fibular pain in addition to medial ankle pain. This is an unstable ankle injury.
  • Tibial plafond fractures will have tenderness along the distal tibial and may have severely decreased range of motion in the ankle.

Causes

  • Direct forces such as those caused by falls and MVCs
  • Indirect or rotational forces



Ankle Injury, Soft Tissue
Compartment Syndrome, Extremity
Fractures, Ankle
Fractures, Knee
Knee Injury, Soft Tissue
Pediatrics, Child Abuse
Pediatrics, Limp
Peripheral Vascular Injuries
Trauma, Peripheral Vascular Injuries

Other Problems to be Considered

Shin splints
Stress fracture



Imaging Studies

  • Perform radiographs of the knee, tibia/fibula, and ankle as indicated.
  • Computed tomography
    • Computed tomography is indicated for severely injured patients if unable to get diagnostically sufficient radiographs of the knee. 
    • In patients with tibial plateau fractures and tibial plafond fractures, computed tomography can help further evaluate the extent of the fracture. 
    • In tibial plateau fractures, radiographs may underestimate the degree of articular depression when compared with computed tomography. This is important because articular depression of greater than 3 mm may be considered for surgery.
  • For stress fractures
    • Radiographic findings are usually seen after 2-8 weeks of symptoms, and radiographs may not be very sensitive during the early stages of symptoms.
    • Radionucleotide scanning and MRI are more sensitive in diagnosing stress fractures and stress injuries than radiographs.



Prehospital Care

  • Address airway, breathing, and circulation.
  • Check and document neurovascular status.
  • Apply sterile dressing to open wounds.
  • Apply gentle traction to reduce gross deformities; splint the extremity.
  • Administer parenteral analgesics for an isolated extremity injury in a hemodynamically stable patient.

Emergency Department Care

  • Open fractures must be diagnosed and treated appropriately. Tetanus should be updated and appropriate antibiotics given. This should involve antistaphylococcal coverage and consideration of an aminoglycoside for more severe wounds. Orthopedics should be consulted for emergent debridement and wound care. Fractures with tissue at risk for opening should be protected to prevent further morbidity.
  • Compartment syndrome can develop in fractures of the lower leg.
    • Signs of compartment syndrome include crescendo symptoms, pain with passive movement of involved muscles, paresthesias, and pallor, and a very late finding is pulselessness. Increased compartment pressure is present during compartment syndrome; therefore, external palpation frequently aids in the diagnosis. However, a soft extremity on palpation does not rule out compartment syndrome.
    • Serial examinations should be performed on patients with high-risk injuries or patients with equivocal symptoms.
    • If compartment syndrome is suspected, obtain an emergent orthopedic consult and measure compartment pressures. Compartment syndrome must be treated promptly with an emergency surgical fasciotomy. If untreated, the increased compartment pressures can cause ischemia and necrosis of the structures within that facial compartment and permanent disability.
  • Tibial plateau fracture
    • Immobilize nondisplaced fractures and have the patient remain nonweightbearing.
    • Obtain an orthopedic consultation for displaced (depressed) fractures, which require open reduction and internal fixation. Articular depression of greater than 3 mm may be considered for surgery.
  • Tibial eminence fracture
    • For nondisplaced fractures (and stable knee joint), immobilize the knee.
    • Obtain an orthopedic consultation for an unstable knee, or displaced fracture for possible surgical fixation.
  • Tibial tubercle fracture
    • For nondisplaced fractures, immobilize the knee.
    • Obtain an orthopedic consultation for a displaced fracture to consider open reduction and internal fixation.
  • Proximal tibia fractures
    • Intra-articular fractures require reduction and internal fixation.
    • Other methods to surgically repair proximal tibia fractures include external fixation, plating, and intramedullary nailing.
    • Closed treatment involves reduction and the placement of a long leg cast. Intact extensor mechanisms can make it difficult to maintain good fracture alignment.
  • Tibial shaft fractures that are closed may be treated with cast immobilization if alignment is good or with intramedullary nailing.
  • Isolated midshaft or proximal fibula fracture
    • Immobilization in a long leg cast generally is not required. Recommend a few days without weightbearing activity until swelling resolves, followed by weightbearing activity as tolerated.
    • Short leg walking cast usually is not required; however, some orthopedists may prefer a short leg walking cast or cam walker with weight bearing.
  • Tibia and fibula stress fractures
    • The keystone of treating stress fractures is the temporary cessation of the offending activity.
    • Crutches may be used initially to allow the patient to be nonweight-bearing.

Consultations

  • Tibia and fibula fractures
    • Obtain emergent orthopedic consultation for open fractures.
    • Consultation is also generally indicated for closed fractures.
  • Emergent consultation is needed in suspected compartment syndrome.
  • Advise patient to obtain orthopedic follow-up care of isolated fibula fractures.



Drugs used to treat fractures include nonsteroidal anti-inflammatory agents and analgesics. In addition, administer proper antibiotics and tetanus prophylaxis for open fractures.

Drug Category: Nonsteroidal anti-inflammatory agents (NSAIDs)

These drugs have analgesic and antipyretic activities. Their mechanism of action is not known, but they may inhibit cyclooxygenase activity and prostaglandin synthesis. Other mechanisms may involve inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation, and various cell-membrane functions.

Drug NameIbuprofen (Ibuprin, Advil, Motrin)
DescriptionUsually DOC for treatment of mild to moderately severe pain, if no contraindications. Inhibits inflammatory reactions and pain, probably by decreasing activity of enzyme cyclooxygenase, which decreases prostaglandin synthesis.
Adult Dose200-400 mg PO q4-6h prn; not to exceed 3.2 g/d
Pediatric Dose<6 months: Not established
6 months to 12 years: 20-40 mg/kg/d PO divided tid/qid
>12 years: Administer as in adults
ContraindicationsDocumented hypersensitivity; peptic ulcer disease; recent GI bleeding or perforation; renal insufficiency; high risk of bleeding
InteractionsAspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity; may decrease effects of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT in patients taking anticoagulants—monitor PT closely and instruct patients to watch for signs of bleeding; may increase risk of methotrexate toxicity; may increase phenytoin levels
PregnancyB - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals
D - Fetal risk shown in humans; use only if benefits outweigh risk to fetus
PrecautionsCaution in congestive heart failure, hypertension, and decreased renal and hepatic function; caution in coagulation abnormalities or during anticoagulant therapy

Drug NameNaproxen (Anaprox, Naprelan, Naprosyn)
DescriptionUsed for relief of mild to moderately severe pain. Inhibits inflammatory reactions and pain by decreasing activity of enzyme cyclooxygenase, decreasing prostaglandin synthesis.
Adult Dose500 mg PO followed by 250 mg q6-8h; not to exceed 1.25 g/d
Pediatric Dose<2 years: Not established
>2 years: 5-7 mg/kg/dose PO q8-12h
ContraindicationsDocumented hypersensitivity; peptic ulcer disease; recent GI bleeding or perforation; renal insufficiency
InteractionsAspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity; may decrease effects of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT in patients taking anticoagulants—monitor PT closely and instruct patients to watch for signs of bleeding; may increase risk of methotrexate toxicity; may increase phenytoin levels
PregnancyB - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals
D - Fetal risk shown in humans; use only if benefits outweigh risk to fetus
PrecautionsAcute renal insufficiency, interstitial nephritis, hyperkalemia, hyponatremia, and renal papillary necrosis may occur; patients with preexisting renal disease or compromised renal perfusion risk acute renal failure; leukopenia occurs rarely, is transient, and usually returns to normal during therapy; persistent leukopenia, granulocytopenia, or thrombocytopenia warrants further evaluation and may require discontinuation of drug

Drug Category: Analgesics

Pain control is essential to quality patient care. It ensures patient comfort, promotes pulmonary toilet, and aids physical therapy regimens. Many analgesics have sedating properties that benefit patients who have sustained fractures.

Drug NameAcetaminophen (Tylenol, Panadol, aspirin-free Anacin)
DescriptionDOC for treatment of pain in patients with documented hypersensitivity to aspirin or NSAIDs, with upper GI disease, or taking oral anticoagulants.
Adult Dose325-650 mg PO q4-6h or 1000 mg tid/qid; not to exceed 4 g/d
Pediatric Dose<12 years: 10-15 mg/kg/dose PO q4-6h prn; not to exceed 2.6 g/d
>12 years: 325-650 mg PO q4h; not to exceed 5 doses in 24 h
ContraindicationsDocumented hypersensitivity; known G-6-P deficiency
InteractionsRifampin can reduce analgesic effects; barbiturates, carbamazepine, hydantoins, and isoniazid may increase hepatotoxicity
PregnancyB - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals
PrecautionsHepatotoxicity possible in chronic alcoholics following various dose levels; severe or recurrent pain or high or continued fever may indicate a serious illness; acetaminophen is contained in many OTC products and combined use with these products may result in cumulative acetaminophen doses exceeding recommended maximum dose

Drug NameAcetaminophen and codeine (Tylenol #3)
DescriptionDrug combination indicated for treatment of mild to moderately severe pain.
Adult Dose30-60 mg/dose based on codeine content PO q4-6h or 1-2 tab q4h; not to exceed 12 tab/d
Pediatric Dose0.5-1 mg/kg/dose based on codeine content PO q4-6h; 10-15 mg/kg/dose based on acetaminophen content; not to exceed 2.6 g/d of acetaminophen
ContraindicationsDocumented hypersensitivity
InteractionsCNS depressants or tricyclic antidepressants increase toxicity
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
PrecautionsCaution in patients dependent on opiates since this substitution may result in acute opiate-withdrawal symptoms; caution in severe renal or hepatic dysfunction

Drug NameHydrocodone bitartrate and acetaminophen (Vicodin ES)
DescriptionDrug combination indicated for relief of moderately severe to severe pain.
Adult Dose1-2 tab/cap PO q4-6h prn
Pediatric Dose<12 years: 10-15 mg/kg/dose acetaminophen PO q4-6h prn; not to exceed 2.6 g/d of acetaminophen
>12 years: 750 mg acetaminophen q4h; single dose not to exceed 10 mg of hydrocodone bitartrate; not to exceed 5 doses/d
ContraindicationsDocumented hypersensitivity; high-altitude cerebral edema; elevated intracranial pressure
InteractionsPhenothiazines may decrease analgesic effects; CNS depressants or tricyclic antidepressants increase toxicity
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
PrecautionsTablets contain metabisulfite, which may cause hypersensitivity; caution in patients dependent on opiates since this substitution may result in acute opiate-withdrawal symptoms; caution in severe renal or hepatic dysfunction

Drug NameOxycodone and acetaminophen (Percocet)
DescriptionDrug combination indicated for relief of moderately severe to severe pain. DOC for aspirin-hypersensitive patients.
Adult Dose1-2 tab/cap PO q4-6h prn
Pediatric Dose0.05-0.15 mg/kg/dose oxycodone PO q4-6h prn; not to exceed 5 mg/dose oxycodone
ContraindicationsDocumented hypersensitivity
InteractionsPhenothiazines may decrease analgesic effects; CNS depressants or tricyclic antidepressants increase toxicity
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
PrecautionsDuration of action may increase in elderly persons; be aware of total daily dose of acetaminophen patient is receiving; do not exceed 4000 mg/24 h of acetaminophen; higher doses may cause liver toxicity

Drug NameMorphine sulfate (Duramorph, Astramorph, MS Contin)
DescriptionDOC for narcotic analgesia because of its reliable and predictable effects, safety, and ease of reversibility with naloxone. Administered IV, may be dosed in a number of ways and commonly is titrated until desired effect obtained.
Adult DoseStarting dose: 0.1 mg/kg IV/IM/SC
Maintenance dose: 5-20 mg/70 kg IV/IM/SC q4h
Relatively hypovolemic patients: Start with 2 mg IV/IM/SC, and reassess hemodynamic effects of dose
Pediatric DoseNeonates: 0.05-0.2 mg/kg IV/IM/SC q2-4h prn
Children: 0.1-0.2 mg/kg IV/IM/SC q2-4h prn
ContraindicationsDocumented hypersensitivity; hypotension; potentially compromised airway in which establishing rapid airway control would be difficult
InteractionsPhenothiazines may antagonize analgesic effects; tricyclic antidepressants, MAOIs, and other CNS depressants may potentiate adverse effects
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
PrecautionsAvoid in hypotension, respiratory depression, nausea, emesis, constipation, and urinary retention; caution in atrial flutter and other supraventricular tachycardias; has vagolytic action and may increase ventricular response rate

Drug Category: Immunoglobulins

Patients who may not have been immunized against Clostridium tetani products should receive tetanus immune globulin.

Drug NameTetanus immune globulin (Hyper-Tet)
DescriptionUsed for passive immunization of any person with a wound that may be contaminated with tetanus spores.
Adult DoseProphylaxis: 250-500 U IM in opposite extremity to tetanus toxoid
Clinical tetanus: 3,000-10,000 U IM
Pediatric DoseProphylaxis: 250 U IM in opposite extremity to tetanus toxoid
Clinical tetanus: Administer as in adults
ContraindicationsSince antibodies in globulin preparation may interfere with immune response to vaccination, do not administer within 3 mo of live virus immune globulin administration; may be necessary to revaccinate persons who received immune globulin shortly after live virus vaccination
InteractionsNone reported
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
PrecautionsPersons with isolated IgA deficiency have potential for developing antibodies to IgA and could have anaphylactic reactions to subsequent administration of blood products that contain IgA; do not perform skin testing since intradermal injection of concentrated gamma globulin may cause localized area of inflammation and can be misinterpreted, causing medication to be withheld from patient not allergic to this material; true allergic responses to human gamma globulin given in prescribed IM manner are extremely rare; do not admix with other medications since usually incompatible

Drug Category: Toxoids

This agent is used for tetanus immunization. Booster injection in previously immunized individuals is recommended to prevent this potentially lethal syndrome.

Drug NameTetanus toxoid
DescriptionUsed to induce active immunity against tetanus in selected patients. Tetanus and diphtheria toxoids are immunizing AOC for most adults and children >7 y. Necessary to administer booster doses to maintain tetanus immunity throughout life.
Pregnant patients should receive only tetanus toxoid, not a diphtheria antigen-containing product.
In children and adults, may administer into the deltoid or midlateral thigh muscles. In infants, preferred site of administration is midthigh laterally.
Adult DosePrimary immunization: 0.5 mL IM; give 2 injections 4-8 wk apart and a third dose 6-12 mo after second injection
Booster dose: 0.5 mL q10y
Pediatric DoseAdminister as in adults
ContraindicationsDocumented hypersensitivity; history of any type of neurological symptoms or signs following administration of this product
FDA recommends that elective tetanus immunization be deferred during any outbreak of poliomyelitis because tetanus toxoid injections are important cause of provocative poliomyelitis
InteractionsPatients receiving immunosuppressants, including corticosteroids or radiation therapy, may remain susceptible despite immunization due to poor immune response; cimetidine may enhance or augment delayed-hypersensitivity responses to skin-test antigens; avoid concurrent use of chloramphenicol since it may impair amnestic response to tetanus toxoid; concurrent use of tetanus immune globulin may delay development of active immunity by several days (interaction is nevertheless clinically insignificant and does not preclude its concurrent use)
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
PrecautionsDo not use to treat actual tetanus infections, or for immediate prophylaxis of unimmunized individuals (use instead tetanus antitoxin, preferably human tetanus immune globulin); diminished antibody response to active immunization may be seen in patients receiving immunosuppressive therapy; better to defer primary diphtheria immunization until immunosuppressive therapy discontinued; routine immunization of symptomatic and asymptomatic HIV-infected persons recommended



Further Inpatient Care

  • Tibia and fibula fractures
    • Open fractures require debridement and irrigation in operating room.
    • Inpatient admission may be advised to observe development of compartment syndrome.

Further Outpatient Care

  • Patient should see primary care physician or be referred to an orthopedic surgeon within 1 week for further evaluation and treatment of isolated fibula fractures.

Transfer

  • Transfer is reasonable if approved by patient (for insurance or other reasons) or if a hospital bed or an orthopedic surgeon is unavailable at the transferring institution.

Complications

  • Neurovascular compromise
  • Compartment syndrome
  • Peroneal nerve injury
  • Infection
  • Gangrene
  • Osteomyelitis
  • Delayed union, nonunion, or malunion
  • Amputation or skin loss
  • Posttraumatic arthritis
  • Fat embolism

Prognosis

  • Tibia and fibula fractures
    • Prognosis is generally good yet is dependent on degree of soft-tissue injury and bony comminution.
    • Prognosis is good for isolated fibula fractures.

Patient Education



Medical/Legal Pitfalls

  • Failure to recognize and treat associated life-threatening injuries
  • Failure to consider ankle injury with proximal fibula fracture (Maisonneuve fracture)
  • Failure to recognize open injuries and obtain timely orthopedic consultation
  • Failure to recognize compartment syndrome

Special Concerns

  • Toddler fracture
    • Typically, this type of fracture is nondisplaced spiral fracture of distal tibia unrelated to child abuse.
    • Midshaft tibial fractures, unrelated to a history of major trauma, should alert emergency physician to possibility of child abuse.



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Fracture, Tibia and Fibula excerpt

Article Last Updated: Mar 11, 2008