Continually Updated Clinical Reference
 
 
  All Sources     eMedicine     Medscape     Drug Reference     MEDLINE
 
eMedicine - Fracture, Forearm : Article by

Quick Find
Authors & Editors
Introduction
Clinical
Differentials
Workup
Treatment
Medication
Follow-up
Miscellaneous
Acknowledgments
Multimedia
References

Related Articles
Dislocations, Elbow

Dislocations, Hand

Dislocations, Wrist

Fractures, Elbow

Fractures, Hand

Fractures, Wrist




Patient Education
Breaks, Fractures, and Dislocations Center

Broken Arm Overview

Broken Arm Causes

Broken Arm Symptoms

Broken Arm Treatment




Author: Joneigh Slaughter Khaldun, MD, Resident Physician, Department of Emergency Medicine, State University of New York Medical Center, Kings County Hospital

Joneigh Slaughter Khaldun is a member of the following medical societies: Society for Academic Emergency Medicine

Coauthor(s): Robert J Gore, MD, Clinical Assistant Professor, Attending Physician, Assistant Residency Director, Department of Emergency Medicine, Kings County/State University of New York Downstate Hospital

Editors: Francis Counselman, MD, Program Director, Chair, Professor, Department of Emergency Medicine, Eastern Virginia Medical School; Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine; Tom Scaletta, MD, Past-President, American Academy of Emergency Medicine; Chairperson, Department of Emergency Medicine, Edward Hospital; Assistant Professor of Emergency Medicine, Rush Medical College and Cook County Hospital; John D Halamka, MD, MS, Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center; Rick Kulkarni, MD, Medical Director, Assistant Professor of Surgery, Section of Emergency Medicine, Yale-New Haven Hospital

Author and Editor Disclosure

Synonyms and related keywords: forearm fracture, broken forearm, broken arm, arm fracture, limb fractures, limb fracture, fractured forearm, proximal forearm fractures, middle forearm fractures, forearm shaft fractures, distal shaft forearm fractures, osteoporosis



Background

The forearm, which consists of the radius and ulna, is essentially 2 conelike structures in parallel that are connected at their proximal and distal ends by joint capsules and along their shafts by a fibrous interosseus membrane.1 Fractures of the forearm are classified as involving the proximal, middle, or distal shaft. Injuries to this area are intimately associated with the elbow and wrist and are discussed in those articles (see Differentials). The upper extremity is the most commonly injured extremity; thus, it is imperative that emergency physicians are familiar with the appropriate evaluation and management.   

The pediatric musculoskeletal system differs from that of adults. The relatively greater amount of cartilage and collagen reduces the tensile strength of the bone, making propagation of fractures less likely. They are also less identifiable on radiographs. Also unique to children is the growth plate, or physis (see Salter- Harris Fractures). Depending on the severity of the injury, these fractures can significantly impair further growth and functioning of the limb. 

Pathophysiology

Fractures of both the radius and ulna together are usually the result of a fall onto an outstretched hand (FOOSH) injury. Injuries can also occur as the result of a direct blow. 

For a related CME activity, see CME - Calcium Supplementation May Reduce Fracture Risk.

Frequency

United States

The upper extremity is involved in nearly half of all fractures seen, and wrist fractures account for about one third of these. Specifically, fractures of the forearm account for 10-45% of pediatric fractures, the majority occurring distally.2 In a recent study looking at injuries relating to skate-boarding, fractures of the radius and ulna (or both) was the most common injury (48.2%).3

Mortality/Morbidity

Because of osteoporosis, postmenopausal women have a higher rate of forearm fractures than other adults. When the mechanism of injury seems trivial, suspect a pathologic fracture associated with a cyst or a tumor. Forearm fractures in older persons are associated with increased risk of future vertebral and hip fractures.

Race

Forearm fractures are less common in blacks because of a lower incidence of osteoporosis.

Sex

  • In infants and toddlers, forearm fractures have no sex predilection.
  • In children older than 2 years, fractures are more common in boys than in girls.
  • In older persons, fractures are more common in women than in men.



History

History is usually consistent with a direct blow to the forearm or a fall directly onto the forearm or outstretched hand. Understanding the mechanism of injury helps direct the physical examination to detect injuries.

Physical

  • Patients usually have localized pain, tenderness, and swelling at the fracture site.
  • Fractures are classified as open or closed.
    • Consider any puncture or break in the skin over a fracture site evidence of an open fracture unless proven otherwise.
    • Infection is commonly seen with open fractures and warrants emergent orthopedic evaluation.
    • Incidence of open forearm fractures is second only to those of the tibia.
    • Open fracture classification system4, 5
      • Type I - Puncture wound less than 1 cm, minimal contamination
      • Type II - Laceration greater than 1 cm; moderate soft tissue damage; adequate bone coverage
      • Type IIIA - Extensive soft tissue damage, often high energy with massive contamination and adequate bone coverage
      • Type IIIB - Extensive soft tissue damage with bone exposure, flap coverage usually required
      • Subtype IIIC - Arterial injury requiring repair
    • The Gustilo classification system has significant interuser variability; the extent of the wound is often indeterminable until intraoperative exploration.
  • Perform a neurologic examination.
    • Evaluate sensory function by 2-point discrimination.
    • Assess motor function by having the patient make the following maneuvers: "OK" sign tests median nerve, extending the fingers or wrist against resistance tests radial nerve, and separating the fingers against resistance tests the ulnar nerve.
    • Tendons or muscle bellies entrapped in fracture fragments may account for unusual functional deficits.
  • Perform a vascular examination. Check capillary refill, radial pulse, and Allen test.
  • Examine the wrist and elbow for tenderness and range of motion.
    • Palpate the wrist to evaluate for ulnar styloid fracture, dorsal prominence of the ulna, or wrist pain with rotation.
    • Tenderness or prominence of the radial head may be the only physical finding in patients with reduced Monteggia lesion or radial head fracture.

Causes

  • Sports, particularly in-line skating, skateboarding, scooter riding, mountain biking, and contact sports
  • Trauma, commonly from automobile collisions, blows with a blunt object, or child abuse



Dislocations, Elbow
Dislocations, Hand
Dislocations, Wrist
Fractures, Elbow
Fractures, Hand
Fractures, Wrist


Imaging Studies

  • General radiography principles
    • Anteroposterior and lateral views of the wrist, forearm, and elbow are required when forearm fracture is suspected from clinical findings.
    • Forearm radiographs, which include distal joints, are inadequate for absolutely excluding associated wrist and elbow injuries, as diagnosis of radioulnar dislocation requires the x-ray beam to be centered at the joint.
  • Nightstick fracture: Defined as an isolated midshaft ulnar fracture, usually as a result of the forearm being held in protection across the face. It can also occur with excessive supination or pronation. These require orthopedic referral and can be immobilized with a long-arm splint with 90 degrees of elbow flexion and the hand in a neutral position. Some authors advocate that after 1 week the splint or cast be replaced by a prefabricated functional brace, which allows better wrist mobility and return to function.6 Open reduction and internal fixation (ORIF) becomes necessary when displacement greater than 5 mm or angulation greater than 10º persists.
  • Monteggia fracture
    • Monteggia fracture is defined as a fracture of the ulna (usually proximal one third) with dislocation of the radial head. Anterior radial head dislocation is most common (60%), yet medial, lateral, and posterior dislocations also occur.
    • Isolated proximal ulnar fractures are rare. Always suspect a Monteggia fracture/dislocation, and closely examine radial head for dislocation or other evidence of injury.
    • Radial head dislocation can be missed when radiographs are misinterpreted, falsely negative, or inadequate. It also may go unrecognized when the dislocation reduces spontaneously prior to imaging. A line drawn through the radial shaft and head must align with the capitellum in all views to exclude dislocation.
    • Immobilize with a long-arm splint (with elbow flexed 90° and forearm neutral). Children may be treated by reduction and casting, while adults require admission for ORIF.
  • Galeazzi fracture
    • Galeazzi fracture is defined as a fracture of the distal one third of the radius with dislocation of the distal radioulnar joint (DRUJ). It is also known as a reverse Monteggia fracture.
    • Galeazzi fracture is 3 times more common than Monteggia lesion.
    • Disruption of the DRUJ when overlooked results in a higher rate of morbidity.
    • Shortening of the radius by 5 mm, fracture of the base of the ulnar styloid, widening of DRUJ space by 2 mm, or subluxation of DRUJ all are associated with DRUJ pathology.
    • Obtaining comparison views of the uninjured wrist may be helpful.
    • A 10-20° rotation from normal radiographic position may give false-negative or false-positive readings for DRUJ dislocation.
    • Immobilize with a long-arm splint (with elbow flexed 90° and forearm pronated). Treatment requires admission for an ORIF.
  • Concomitant radius and ulna fractures: Concomitant fractures usually result from a significant force applied directly to the forearm or major multisystem trauma. Swelling and deformity indicate the diagnosis, and radiographic confirmation is usually straightforward (see Media file 1). Compartment syndrome is a potential complication because of the degree of tissue injury and swelling involved. Treatment usually requires admission for an urgent ORIF, though in children younger than 10 years, if reduced to less than 10° of angulation, these fractures may be treated by casting alone.
  • Essex-Lopresti fracture: This is defined as a fracture of the radial head and dislocation of DRUJ, with partial or complete disruption of the radioulnar interosseous membrane.
  • Torus (greenstick) fracture: This occurs in children with only a moderate degree of trauma and can be managed with a long-arm cast for 4-6 weeks when angulation is less than 10° (see Media files 2-3). All require orthopedic referral.



Prehospital Care

Stabilize the arm to prevent or limit neurovascular injury from sharp bone fragments.

Emergency Department Care

  • Immobilize the forearm and upper arm and provide effective analgesia unless the patient has other injuries with the potential for hemodynamic or respiratory instability.
  • Identify other injuries. Because forearm fractures require considerable force, perform a complete physical examination to exclude other injuries.
  • Assess the injured forearm.
    • Perform a careful examination of the upper extremity to identify neurovascular deficits, tense muscle compartments, and disruptions of the skin.
    • Obtain appropriate radiographs to define fracture(s) and evaluate for associated dislocation.
  • Treat injury expeditiously.
  • Provide adequate analgesia/anesthesia.
  • Perform emergent reduction, if necessary. The bone ends may shift, resulting in the loss of reduction. This may occur in the first 10-14 days, or it may occur 6-8 weeks later.
  • Immobilize injury.
  • Administer antibiotics and tetanus immunization, as indicated.
  • Immediate fracture reduction is indicated when any of the following exists:
    • Neurovascular compromise
    • Severe displacement
    • Tenting of the skin
  • ED anesthesia/analgesia options
    • Axillary block provides complete anesthesia and muscle relaxation but carries the risk of arterial or nerve injury.
    • Hematoma block provides anesthesia and muscle relaxation but carries the risk of osteomyelitis.
    • Intravenous regional anesthesia (Bier block) provides anesthesia and muscle relaxation but carries the risk of lidocaine toxicity.
    • Conscious sedation provides effective anesthesia, muscle relaxation, and amnesia. It carries the risk of respiratory depression and requires increased nursing time.

Consultations

  • Consult an orthopedist for open fractures, operative fractures, or dislocations, and arrange close follow-up care.
  • Fracture reductions typically are deferred to an orthopedist unless evidence of neurovascular compromise is noted.
  • Insufficient evidence exists to support a specific management technique of isolated fractures of the ulna.
  • Some evidence indicates that distal radius fractures may have better outcomes with external fixation or pinning than with conservative, nonsurgical management.



Drugs used to treat fractures are generally NSAIDs and analgesics. In addition, administer proper antibiotics and tetanus prophylaxis for open fractures.

Drug Category: Nonsteroidal anti-inflammatory agents (NSAIDs)

These drugs are used most commonly for relief of mild to moderately severe pain. Although effects of NSAIDs in the treatment of pain tend to be patient specific, ibuprofen is usually the DOC for initial therapy. Other options include flurbiprofen, ketoprofen, and naproxen.

Drug NameIbuprofen (Ibuprin, Advil, Motrin)
DescriptionUsually DOC for treatment of mild to moderately severe pain, if no contraindications. Inhibits inflammatory reactions and pain, probably by decreasing activity of enzyme cyclooxygenase, inhibiting prostaglandin synthesis.
Adult Dose200-400 mg PO q4-6h prn; not to exceed 3.2 g/d
Pediatric Dose6 months to 12 years: 20-40 mg/kg/d PO divided tid/qid
>12 years: Administer as in adults
ContraindicationsDocumented hypersensitivity; peptic ulcer disease; recent GI bleeding or perforation; renal insufficiency; high risk of bleeding
InteractionsAspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity; may decrease effects of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT in patients taking anticoagulants—monitor PT closely and instruct patients to watch for signs of bleeding; may increase risk of methotrexate toxicity; may increase phenytoin levels
PregnancyB - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals
D - Fetal risk shown in humans; use only if benefits outweigh risk to fetus
PrecautionsCaution in congestive heart failure, hypertension, and decreased renal and hepatic function; caution in coagulation abnormalities or during anticoagulant therapy

Drug NameKetoprofen (Oruvail, Orudis, Actron)
DescriptionUsed for relief of mild to moderately severe pain and inflammation. Administer small dosages initially to patients with small bodies, older persons, and those with renal or liver disease. Doses higher than 75 mg do not increase therapeutic effects. Administer high doses with caution and closely observe.
Adult Dose25-50 mg PO q6-8h prn; not to exceed 300 mg/d
Pediatric Dose3 months to 12 years: 0.1–1 mg/kg PO q6-8h
>12 years: Administer as in adults
ContraindicationsDocumented hypersensitivity
InteractionsAspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity; may decrease effects of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT in patients taking anticoagulants—monitor PT closely and instruct patients to watch for signs of bleeding; may increase risk of methotrexate toxicity; may increase phenytoin levels
PregnancyB - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals
D - Fetal risk shown in humans; use only if benefits outweigh risk to fetus
PrecautionsCaution in congestive heart failure, hypertension, and decreased renal and hepatic function; caution in coagulation abnormalities or during anticoagulant therapy

Drug NameNaproxen (Anaprox, Naprelan, Naprosyn)
DescriptionUsed for relief of mild to moderately severe pain. Inhibits inflammatory reactions and pain by decreasing activity of enzyme cyclooxygenase, decreasing prostaglandin synthesis.
Adult Dose500 mg PO followed by 250 mg q6-8h; not to exceed 1.25 g/d
Pediatric Dose<2 years: Not established
>2 years: 2.5 mg/kg/dose PO; not to exceed 10 mg/kg/d
ContraindicationsDocumented hypersensitivity; peptic ulcer disease; recent GI bleeding or perforation; renal insufficiency
InteractionsAspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity; may decrease effects of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT in patients taking anticoagulants—monitor PT closely and instruct patients to watch for signs of bleeding; may increase risk of methotrexate toxicity; may increase phenytoin levels
PregnancyB - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals
D - Fetal risk shown in humans; use only if benefits outweigh risk to fetus
PrecautionsAcute renal insufficiency, interstitial nephritis, hyperkalemia, hyponatremia, and renal papillary necrosis may occur; patients with preexisting renal disease or compromised renal perfusion risk acute renal failure; leukopenia occurs rarely, is transient, and usually returns to normal during therapy; persistent leukopenia, granulocytopenia, or thrombocytopenia warrants further evaluation and may require discontinuation of drug

Drug NameFlurbiprofen (Ansaid, Ocufen)
DescriptionHas analgesic, antipyretic, and anti-inflammatory effects. May inhibit cyclooxygenase enzyme, inhibiting prostaglandin biosynthesis.
Adult Dose200-300 mg/d PO divided bid/qid
Pediatric DoseNot established
ContraindicationsDocumented hypersensitivity
InteractionsAspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity; may decrease effects of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT in patients taking anticoagulants—monitor PT closely and instruct patients to watch for signs of bleeding; may increase risk of methotrexate toxicity; may increase phenytoin levels
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
D - Fetal risk shown in humans; use only if benefits outweigh risk to fetus
PrecautionsAcute renal insufficiency, interstitial nephritis, hyperkalemia, hyponatremia, and renal papillary necrosis may occur; patients with preexisting renal disease or compromised renal perfusion risk acute renal failure; leukopenia occurs rarely, is transient, and usually returns to normal during therapy; persistent leukopenia, granulocytopenia, or thrombocytopenia warrants further evaluation and may require discontinuation of drug

Drug Category: Analgesics

Pain control is essential to quality patient care. It ensures patient comfort, promotes pulmonary toilet, and enables physical therapy regimens. Many analgesics have sedating properties that benefit patients who have sustained fractures.

Drug NameAcetaminophen and codeine (Tylenol #3)
DescriptionDrug combination indicated for treatment of mild to moderately severe pain.
Adult Dose30-60 mg/dose based on codeine content PO q4-6h or 1-2 tab q4h; not to exceed 12 tab/d
Pediatric Dose0.5-1 mg/kg/dose based on codeine PO q4-6h; 10-15 mg/kg/dose based on acetaminophen content; not to exceed 2.6 g/d of acetaminophen
ContraindicationsDocumented hypersensitivity
InteractionsCNS depressants or tricyclic antidepressants increase toxicity
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
PrecautionsCaution in patients dependent on opiates because this substitution may result in acute opiate-withdrawal symptoms; caution in severe renal or hepatic dysfunction

Drug NameHydrocodone bitartrate and acetaminophen (Vicodin ES)
DescriptionDrug combination indicated for relief of moderately severe to severe pain.
Adult Dose1-2 tab/cap PO q4-6h prn
Pediatric Dose<12 years: 10-15 mg/kg/dose acetaminophen PO q4-6h prn; not to exceed 2.6 g/d of acetaminophen
>12 years: 750 mg acetaminophen PO q4h; single dose not to exceed 10 mg of hydrocodone bitartrate; not to exceed 5 doses/d
ContraindicationsDocumented hypersensitivity; high-altitude cerebral edema; elevated intracranial pressure
InteractionsPhenothiazines may decrease analgesic effects; CNS depressants or tricyclic antidepressants increase toxicity
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
PrecautionsTablets contain metabisulfite which may cause hypersensitivity; caution in patients dependent on opiates because this substitution may result in acute opiate-withdrawal symptoms; caution in severe renal or hepatic dysfunction

Drug NameOxycodone and acetaminophen (Percocet)
DescriptionDrug combination indicated for relief of moderately severe to severe pain. DOC for aspirin-hypersensitive patients.
Adult Dose1-2 tab/cap PO q4-6h prn
Pediatric Dose0.05-0.15 mg/kg/dose oxycodone PO q4-6h prn; not to exceed 5 mg/dose of oxycodone q4-6h
ContraindicationsDocumented hypersensitivity
InteractionsPhenothiazines may decrease analgesic effects; CNS depressants or tricyclic antidepressants increase toxicity
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
PrecautionsDuration of action may increase in elderly persons; be aware of total daily dose of acetaminophen patient is receiving; do not exceed 4000 mg/24 h of acetaminophen; higher doses may cause liver toxicity

Drug Category: Antibiotics

Empiric antimicrobial therapy must be comprehensive and should cover all likely pathogens in the clinical setting.

Drug NameGentamicin (Gentacidin, Garamycin)
DescriptionAminoglycoside antibiotics used for gram-negative bacterial coverage. Commonly used in combination with both an agent against gram-positive organisms and one that covers anaerobes. Used in conjunction with ampicillin or vancomycin for prophylaxis in patients with open fractures.
Adult Dose1.5 mg/kg IV; not to exceed 80 mg
Pediatric Dose2 mg/kg IV
ContraindicationsDocumented hypersensitivity; non–dialysis-dependent renal insufficiency
InteractionsOther aminoglycosides, cephalosporins, penicillins, and amphotericin B may increase nephrotoxicity; enhances effects of neuromuscular blocking agents, thus prolonged respiratory depression may occur; loop diuretics may increase auditory toxicity—possible irreversible hearing loss of varying degrees may occur (monitor regularly)
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
PrecautionsNarrow therapeutic index (not intended for long-term therapy); caution in renal failure (patient not taking dialysis), myasthenia gravis, hypocalcemia, and conditions that depress neuromuscular transmission; adjust dose in renal impairment

Drug NameAmpicillin (Omnipen, Marcillin)
DescriptionUsed for prophylaxis in patients undergoing dental, oral, or respiratory tract procedures. Interferes with bacterial cell wall synthesis during active replication, causing bactericidal activity against susceptible organisms. This drug is given in place of amoxicillin in patients unable to take medication orally. It is also used along with gentamicin for prophylaxis in patients with open fractures.
Adult Dose2 g IV/IM
Pediatric Dose50 mg/kg IV/IM
ContraindicationsDocumented hypersensitivity
InteractionsProbenecid and disulfiram elevate levels; allopurinol decreases effects and has additive effects on ampicillin rash; may decrease effects of oral contraceptives
PregnancyB - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals
PrecautionsAdjust dose in renal failure; evaluate rash and differentiate from hypersensitivity reaction

Drug NameVancomycin (Vancocin)
DescriptionPotent antibiotic directed against gram-positive organisms and active against enterococcal species. Also useful in treatment of septicemia and skin structure infections. Used in conjunction with gentamicin for prophylaxis in penicillin-allergic patients undergoing GI or GU procedures. May need to adjust the dose in patients with renal impairment.
Adult Dose1 g IV infused over 1 h
Pediatric Dose1.5 mg/kg IV infused over 1 h
ContraindicationsDocumented hypersensitivity
InteractionsErythema, histaminelike flushing, and anaphylactic reactions may occur when administered with anesthetic agents; taken concurrently with aminoglycosides, risk of nephrotoxicity may increase above that with aminoglycoside monotherapy; effects in neuromuscular blockade may be enhanced when coadministered with nondepolarizing muscle relaxants
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
PrecautionsCaution in renal failure, neutropenia; red man syndrome is caused by too rapid IV infusion (dose given over a few min) but rarely happens when dose given over 2 h or by PO or IP route; red man syndrome not an allergic reaction

Drug Category: Toxoid

This agent is used for tetanus immunization. A booster injection in previously immunized individuals is recommended to prevent this potentially lethal syndrome.

Drug NameTetanus toxoid
DescriptionUsed to induce active immunity against tetanus in selected patients. Tetanus and diphtheria toxoids are immunizing AOC for most adults and children >7 y. Necessary to administer booster doses to maintain tetanus immunity throughout life. Pregnant patients should receive only tetanus toxoid, not a diphtheria antigen-containing product. In children and adults, may administer into deltoid or midlateral thigh muscles. In infants, preferred site of administration is midthigh laterally.
Adult DosePrimary immunization: 0.5 mL IM, give 2 injections 4-8 wk apart and a third dose 6-12 mo after a second injection
Booster dose: 0.5 mL q10y
Pediatric DosePrimary immunization: 0.5 mL IM, give 2 injections 4-8 wk apart and a third dose 6-12 mo after the second injection.
Booster dose: 0.5 mL q10y
ContraindicationsDocumented hypersensitivity; history of any type of neurological symptoms or signs following administration of this product
FDA recommends that elective tetanus immunization be deferred during any outbreak of poliomyelitis because tetanus toxoid injections are an important cause of provocative poliomyelitis
InteractionsPatients receiving immunosuppressants, including corticosteroids or radiation therapy, may remain susceptible despite immunization due to poor immune response; cimetidine may enhance or augment delayed-hypersensitivity responses to skin-test antigens; avoid concurrent use of chloramphenicol because it may impair amnestic response to tetanus toxoid; concurrent use of tetanus immune globulin may delay development of active immunity by several days (interaction is nevertheless clinically insignificant and does not preclude its concurrent use)
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
PrecautionsDo not use to treat actual tetanus infections, or for immediate prophylaxis of unimmunized individuals (use instead tetanus antitoxin, preferably human tetanus immune globulin) diminished antibody response to active immunization may be seen in patients receiving immunosuppressive therapy; better to defer primary diphtheria immunization until immunosuppressive therapy discontinued; routine immunization of symptomatic and asymptomatic HIV-infected persons is recommended

Drug Category: Immunoglobulins

Patients who may not have been immunized against Clostridium tetani products should receive tetanus immune globulin.

Drug NameTetanus immune globulins (Hyper-Tet)
DescriptionUsed for passive immunization of any person with a wound that may be contaminated with tetanus spores.
Adult DoseFor prophylaxis: 250-500 U IM in opposite extremity to tetanus toxoid lesion
For clinical tetanus: 3,000-10,000 U IM
Pediatric DoseFor prophylaxis: 250 U IM in the opposite extremity to tetanus toxoid
For clinical tetanus: 3,000-10,000 U IM
ContraindicationsBecause antibodies in globulin preparation may interfere with immune response to vaccination, do not administer within 3 mo of live-virus immune globulin administration; may be necessary to revaccinate persons who received immune globulin shortly after live-virus vaccination
InteractionsNone reported
PregnancyC - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
PrecautionsPersons with isolated IgA deficiency have potential for developing antibodies to IgA and could have anaphylactic reactions to subsequent administration of blood products that contain IgA; do not perform skin testing because intradermal injection of concentrated gamma globulin may cause localized area of inflammation and can be misinterpreted, causing the medication to be withheld from a patient not allergic to this material; true allergic responses to human gamma globulin given in prescribed IM manner are extremely rare; do not admix with other medications because usually incompatible



Further Inpatient Care

  • Admit patient whenever the following conditions are present:
    • Open fracture
    • Presence of or potential for neurovascular compromise
    • Fracture requiring ORIF and orthopedist plans to operate expeditiously

Further Outpatient Care

  • Most cases can be treated safely by splinting and referral to an orthopedist who will then schedule surgical repair (if necessary).
  • Elevate the injured extremity and limit physical activities to prevent further injury.
  • Provide instructional material on cast/splint care and symptoms requiring a return to the ED.

In/Out Patient Meds

  • Prescribe oral analgesics (eg, NSAIDs, acetaminophen with codeine/hydrocodone).

Transfer

  • Transfer to a facility with a higher level of care when no orthopedist is available and admission or urgent surgery is necessary.

Deterrence/Prevention

  • Recommend wearing wrist guards while in-line skating, roller skating, or skateboarding.
  • Prevent osteoporosis in postmenopausal women.

Complications

  • Direct neurovascular injury
  • Physeal arrest if fracture involves the growth plate
  • Radioulnar synostosis after delayed treatment
  • Compartment syndrome - Associated with closed shaft fractures of the radius or ulna and with tight casts. It is less common in upper extremities than in lower extremities.
  • Loss of supination-pronation after a forearm fracture

Prognosis

  • Prognosis for recovery of forearm fractures (ie, good bony union, maintenance of function) is related to severity and type of fracture and is optimized by treating fractures early and appropriately.
  • Morbidity is related to missed or delayed diagnosis of an open fracture or dislocation associated with fracture.
  • Improvements in internal and external fixation materials and techniques have allowed more aggressive treatment of forearm fractures, with fewer complications and improved recovery of function.
  • Midshaft fractures tend to have worse outcomes than fractures in the distal or proximal third of the forearm.

Patient Education



Medical/Legal Pitfalls

  • Failure to suspect DRUJ pathology in the face of isolated radial fracture (Galeazzi type)
  • Failure to suspect radial head dislocation in the face of isolated ulnar fracture (Monteggia type)
    • Radial head dislocations usually can be reduced or closed early in presentation, but delayed diagnosis commonly requires open reduction.
    • Lesions undiagnosed by the emergency physician are likely to be missed on outpatient follow-up visit.
    • Spontaneous reduction during splinting and loss of physical findings of pain at the radial head by the time of follow-up contribute to delayed or missed diagnosis
  • Failure to appreciate an open fracture (attributing wounds to a simple soft-tissue injury)
  • Failure to recognize neurovascular injury

Special Concerns

  • Suspect child abuse when the mechanism of injury is inconsistent with fracture type, especially in newborns and infants.
  • Realize that lesser amounts of mechanical force may result in fracture, especially in postmenopausal women.



The authors and editors of eMedicine gratefully acknowledge the contributions of previous authors, Enoch Huang, MD, and Peter Grimes, MD, to the development and writing of this article.



Media file 1:  Fractures of the radius and ulna with dorsal angulation of distal fragments.
Click to see larger pictureClick to see detailView Full Size Image
Media type:  Radiograph

Media file 2:  Torus fracture of the radius.
Click to see larger pictureClick to see detailView Full Size Image
Media type:  Radiograph

Media file 3:  Torus fracture of the radius.
Click to see larger pictureClick to see detailView Full Size Image
Media type:  Radiograph



  1. Simon RR, Sherman SC, Koenigsknecht SJ. Forearm. In: Emergency Orthopedics: The Extremities. 5th ed. McGraw-Hill; 2007:218-231.
  2. Benjamin H, Hang B. Common Acute Upper Extremity Injuries in Sports. Clin Ped Emerg Med. 8:15-30.
  3. Zalavras C, Nikolopoulou G, Essin D, et al. Pediatric fractures during skateboarding, roller skating, and scooter riding. Am J Sports Med. Apr 2005;33(4):568-73. [Medline].
  4. Gustilo RB, Mendoza RM, Williams DN. Problems in the management of type III (severe) open fractures: a new classification of type III open fractures. J Trauma. Aug 1984;24(8):742-6. [Medline].
  5. Zalavras CG, Patzakis MJ, Holtom PD, et al. Management of open fractures. Infect Dis Clin North Am. Dec 2005;19(4):915-29. [Medline].
  6. Gebuhr P, Holmich P, Orsnes T, et al. Isolated ulnar shaft fractures. Comparison of treatment by a functional brace and long-arm cast. J Bone Joint Surg Br. Sep 1992;74(5):757-9. [Medline].
  7. Anderson LD, Meyer FN, Lippincott JB. Fractures of the shafts of the radius and ulna. In: Rockwood and Green's Fractures in Adults. 3rd ed. Publishers: Lippincott-Raven; 1991:679-737.
  8. Carson S, Woolridge D, Colletti J, et al. Pediatric Upper Extremity Injuries. Ped Clin North Am. 2006;53:41-67.
  9. Cheng JC, Shen WY. Limb fracture pattern in different pediatric age groups: a study of 3,350 children. J Orthop Trauma. 1993;7(1):15-22. [Medline].
  10. Cramer KE, Glasson S, Mencio G, et al. Reduction of forearm fractures in children using axillary block anesthesia. J Orthop Trauma. 1995;9(5):407-10. [Medline].
  11. Eastell R. Forearm fracture. Bone. Mar 1996;18(3 Suppl):203S-207S. [Medline].
  12. Gleeson AP, Beattie TF. Monteggia fracture-dislocation in children. J Accid Emerg Med. Sep 1994;11(3):192-4. [Medline].
  13. Gregory PR, Sullivan JA. Nitrous oxide compared with intravenous regional anesthesia in pediatric forearm fracture manipulation. J Pediatr Orthop. Mar-Apr 1996;16(2):187-91. [Medline].
  14. Handoll HH, Madhok R. Closed reduction methods for treating distal radial fractures in adults. Cochrane Database Syst Rev. 2003;4.
  15. Handoll HH, Madhok R. Surgical interventions for treating distal radial fractures in adults. Cochrane Database Syst Rev. 2003;4.
  16. Handoll HH, Pearce PK. Interventions for isolated diaphyseal fractures of the ulna in adults. Cochrane Database Syst Rev. 2004;CD000523. [Medline].
  17. Kay S, Smith C, Oppenheim WL. Both-bone midshaft forearm fractures in children. J Pediatr Orthop. May-Jun 1986;6(3):306-10. [Medline].
  18. Macule Beneyto F, Arandes Renu JM, Ferreres Claramunt A, et al. Treatment of Galeazzi fracture-dislocations. J Trauma. Mar 1994;36(3):352-5. [Medline].
  19. Metz VM, Gilula LA. Imaging techniques for distal radius fractures and related injuries. Orthop Clin North Am. Apr 1993;24(2):217-28. [Medline].
  20. Morgan WJ, Breen TF. Complex fractures of the forearm. Hand Clin. Aug 1994;10(3):375-90. [Medline].
  21. Newton EJ, Love J. Emergency department management of selected orthopedic injuries. Emerg Med Clin North Am. Aug 2007;25(3):763-93, ix-x. [Medline].
  22. Proust AF, Bredenkamp JH, Uehara DT. Injuries to the elbow and forearm. In: Tintinalli JE, ed. Emergency Medicine: A Comprehensive Study Guide. 6th ed. McGraw Hill Text: 2004:1690-1694.
  23. Singletary EM. Volar dislocation of the distal radioulnar joint. Ann Emerg Med. Apr 1994;23(4):881-3. [Medline].
  24. Younger AS, Tredwell SJ, Mackenzie WG, et al. Accurate prediction of outcome after pediatric forearm fracture. J Pediatr Orthop. Mar-Apr 1994;14(2):200-6. [Medline].
  25. Zautcke JL. Forearm Injuries. In: Hart RG, Rittenberry TJ, eds. Handbook of Orthopaedic Emergencies. Lippincott Williams & Wilkins Publishers: 1999:222-232.

Fracture, Forearm excerpt

Article Last Updated: Jul 11, 2008